Lakanu said she is building a relationship with Clay Court after she defeated Daria Kastakina on Monday.
After the fourth round of the Italian Open at Raducanu, she defeated Kasatkina, the world's No. 17, where she won three consecutive clay games for the first time in her career.
Rado Canu paid off with a solid start to Collins, who led 3-2, and Collins cut increasingly frustrated numbers to deal with rival consistency.
The British won eight straight points in their service to the game and joked with the team when they made only six uncompulsory mistakes in the first 10 games.
However, when Collins broke twice without replying, momentum spun sharply in the second set, while Radanu surpassed her first set error count in Game 4.
Raducanu soon called for physiology and then fell 5-0 and left the court after a brief discussion.
To ease her team, she seemed to be free to move once the game resumed and the game against her ended – but Collins would not be denied.
Lacanu put a huge pressure on her first eight-game breakpoint into ninth place forcing the on-field serve 3-3.
However, the former U.S. Open champion was eliminated in the end stage and was eliminated twice as Collins completed the turnaround after two hours and 20 minutes.
Spain's third seed Paula Badosa and Russia's Liudmila Samsonova are potential semi-final rivals for 2024 runner-up Collins at Strasbourg.
The other quarterfinals saw the second seed of the US, Emma Navarro, facing Brazil's Beatriz Haddad Maia, while the fourth seed of Hazakh, Elena Rybakina, plays Poland's Magda Rybakina.
